In their previous encounter, City secured a resounding 6-2 victory over Luton in the FA Cup, with Erling Haaland netting five goals. Their recent match against Real Madrid showcased another captivating showdown, ending in a dramatic 3-3 draw in the first leg of their Champions League quarter-final.
Despite Bernardo Silva's early goal, Real Madrid responded with two deflected strikes. However, goals from Phil Foden and Josko Gvardiol put City back in front, only for a stunning volley from Federico Valverde to salvage a draw for Real.
Manchester City's prowess is evident, having scored three goals in nine consecutive Champions League games. They're also in contention for multiple trophies this season, including the Premier League title, currently sitting third in the table behind Arsenal and Liverpool.
A win against Luton could momentarily propel City to the top of the Premier League, two points clear of their rivals. They've already beaten Luton twice away from home this season, and their unbeaten streak at the Etihad Stadium, spanning 40 games across all competitions, adds to their confidence.
Luton, meanwhile, ended a 10-game winless streak in the Premier League with a comeback victory against Bournemouth last weekend. Despite their determination, they face an uphill battle against City, acknowledging their underdog status and injury concerns.
Having won just two away games in the Premier League this season, Luton have never triumphed in an away league game against the reigning champions in 16 attempts. Their recent away record against top-flight champions highlights the challenge they'll face at the Etihad.
INJURIES & SUSPENSION
Kyle Walker and Nathan Ake from Manchester City are likely to miss out due to hamstring and calf injuries respectively. There's uncertainty surrounding Phil Foden's availability after he sustained a knock against Real Madrid, although he has provided a positive update on his injury.Kevin De Bruyne was sidelined due to illness in the previous match but should be ready for selection this Saturday. Matheus Nunes, Jeremy Doku, and Julian Alvarez are all contenders for a spot in the squad.
Rodri has expressed the need for a break, and City might opt to rest him against Luton with an eye on the upcoming second leg against Real Madrid. Players like Josko Gvardiol, John Stones, Bernardo Silva, and Erling Haaland could also see reduced minutes.
Luton Town has several players unavailable due to injuries, including Tom Lockyer, Marvelous Nakamba, and Jacob Brown. Gabriel Osho's fitness will be assessed before kickoff, with Daiki Hashioka potentially filling in if Osho is unable to return.
Issa Kabore, on loan from Manchester City, is ineligible to play against his parent club. Tahith Chong and Fred Onyedinma are options for the right wing-back position, while Jordan Clark is expected to feature in midfield alongside Ross Barkley, who scored twice against City in the FA Cup earlier this season.
POSSIBLE LINE-UPS
Manchester City possible starting lineup:Ortega; Akanji, Dias, Gvardiol; Lewis, Kovacic; Doku, De Bruyne, Nunes, Grealish; Haaland
Luton Town possible starting lineup:
Kaminski; Hashioka, Mengi, Burke; Onyedinma, Barkley, Clark, Doughty; Townsend, Chong; Morris
EXPERT PREDICTION
Man City 4-1 Luton
Luton's victory last weekend provided a much-needed lift in their bid to steer clear of relegation, especially after enduring a tough period. However, the challenge of securing consecutive wins for the first time since December and halting Manchester City's dominance on their home ground is undoubtedly daunting.
Manchester City thrives at the Etihad Stadium, and considering their previous success against Luton this season, it's hard to imagine anything other than a convincing win for the title contenders. Even if Guardiola decides to rotate his squad from the midweek fixture, City's strength and home advantage make them clear favorites.