The first leg ended 2-2 at the Nou-Camp, and it was all to play for in the second leg at Old Trafford. Robert Lewandoski opened the scoring for the visitors in the 18th minute via a penalty kick, and Fred leveled up the tie for the home side in the 47th minute from a Bruno Fernandes assist.
Antony scored the decisive goal in the 73rd minute after coming on from the bench to send the Red Devils through to the next round and condemn Barcelona to yet another knock out round exit in European club football.