Jurgen Klopp and Pep Guardiola’s sides have dominated English football in recent years and another blockbuster game is expected from both sides.
The Reds will be hoping to pick up a much-needed win as they sit in 10th position on the table.
They have only won two games so far this season which is their worst start to a campaign for ten years.
City, on the other hand, are the only team not to lose a single competitive game this term.
For many years now this game has been between the top two teams and top two managers in the country and it is set to be another huge occasion at Anfield.
What's your prediction for this blockbuster tie?
Will it be a
Liverpool Win
Manchester City Win
Or Another Entertaining Draw?